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Synuclein-based assay and novel synuclein protein

CA 2244880 A1 · Owner: The University Court Of The University Of St. Andrews · Inventors: Buchman, Vladimir Lvovich; Mccallion, Andrew Smyth; Davies, Alun Millward

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Abstract From the Canadian patent

A novel member of the synuclein family has been identified and is termed persyn. The full amino acid sequence for the mouse and human isoforms are given in SEQ ID Nos 2 and 4, with the respective nucleotide coding sequences being given as SEQ ID Nos 1 and 3. The unusual expression pattern noted for persyn in, neurons and in skin, led to the realisation that synucleins affect intracellular intermediate filament structure. Thus, an assay for cells exhibiting abnormal intermediate filament structure is described based upon evaluation of intracellular synuclein. The assay is special relevance to neurodegenerative disorders characterised by plaque deposition to, cancers (especially breast …

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed September 18, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended September 18, 2018.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 18, 2020.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledSeptember 18, 1998
GrantedNo grant recorded
Term endedSeptember 18, 2018
Patent numberCA 2244880 A1
Classification (IPC)C12N15/12 +2 more

Timeline

Timeline From CIPO dates

1999200120032005200720092011201320152017Application filedSep 18, 1998Term endedSep 18, 2018

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.