Fluorescence detection assay for homogeneous pcr hybridization systems
CA 2243759 C · Owner: Di Cesare, Joseph L. · Inventors: Di Cesare, Joseph L.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
An improved assay system for homogeneous assay detection and/or measuring target nucleic acid sequence replicated in a PCR amplification procedure is provided by employing a nucleic acid polymerase having 5' to 3' exonuclease activity and devoid of 3' to 5' exonuclease activity oligonucleotide , analytical probe blocked against chain extension at its 3' terminus and labeled at its 5' terminus with an energy transfer donor fluorophore and , oligonucleotide detection probe labeled at its 3' terminus with an energy transfer acceptor fluorophore, said probes being complements of each other but differing in nucleotide length so that their Tm's are at least 10 ~C apart the Tm of the …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 31, 1997 and granted May 21, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended January 31, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 31, 2019.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.