Cross-linked polypeptide fragments of .beta.-galactosidase
CA 2241782 C · Owner: Khanna, Pyare · Inventors: Khanna, Pyare; Eisenbeis, Scott J.; Powell, Michael J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Formation of an intramolecular, cross-link in enzyme donor polypeptide fragments of .beta.-galactosidase, thereby forming a cyclic enzyme donor which, is hindered from complementation with an enzyme acceptor fragment to form, active of .beta.-galactosidase. The cyclic enzyme donor can be linearized by, cleaving to restore complementation ability. Assays in which such cyclic, enzyme donors are linearized by specific analytes are disclosed, as well as, novel homobifunctional bis-maleimido cross-linking agents of formula (I), wherein R is hydroxy or acetate.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 23, 1997 and granted April 23, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended January 23, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 23, 2019.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.