A specific and sensitive method to detect prpsc in peripheral blood using a capture-immunosorbent assay-polymerase chain reaction (prp-immuno-pcr)
CA 2237739 A1 · Owner: Tetro, Jason Anthony · Inventors: Tetro, Jason Anthony
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Currently, there is no method to identify with high specificity and sensitivity, the prion, proteins (PrP sc) that lead to the development of the human diseases Cruetzfeldt-Jakob Disease, (CJD) and new variant CJD (nvCJD) also known as bovine spongiform , encephalopathy (BSE). The invention is such a diagnostic assay and hereforth defined as PrP-Immuno- PCR. The method, involves the combination of two well-described techniques to detect as little as one infectious unit, from whole blood using monoclonal antibodies specific to the disease-causing prion proteins and, the polymerase chain reaction to amplify such signal using a novel antibody- DNA complex. The, method also differentiates …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 23, 1998. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended June 23, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 23, 2020.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.