Detection of nucleic acids by fluorescence quenching
CA 2236616 C · Owner: Becton, Dickinson And Company · Inventors: Nadeau, James G.; Walker, G. Terrance; Vonk, Glenn P.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Single-stranded signal primers are modified by linkage to two dyes which form a donor/acceptor dye pair. The two dyes are positioned in sufficiently close spatial proximity on the signal primer that the fluorescence of the first dye is quenched by the second dye. The signal primer may further comprise a restriction endonuclease recognition site (RERS) between the two dyes. As the signal primer is initially single-stranded and remains single-stranded in the absence of target, the restriction endonuclease recognition site is not cleavable or nickable by the restriction endonuclease. In the presence of target however, signal primer and the, restriction endonuclease recognition site are …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 4, 1998 and granted April 23, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended May 4, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 4, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.