Quinoline and quinazoline compounds useful in therapy

Abstract From the Canadian patent

Compounds of formula I, (see fig. I), wherein R1 represents C1-4 alkoxy optionally substituted by one or more fluorine atoms; R2 represents an aryl group or a heteroaryl group optionally substituted by C1-4 alkyl or SO2NH2;, R3 represents a 4-, 5-, 6-. or 7-membered heterocyclic ring containing at least one heteroatom selected from N. O and S, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic ring containing at least one heteroatom selected from N O, and S, the ring system as a whole being optionally substituted; X represents CH or N: and, L is absent or represents a cyclic group of formula Ia. (see fig.Ia) or represents a chain of formula Ib, (see fig.Ib) …