Sensitive detection of cell surface markers on viable cells
CA 2234582 A1 · Owner: Radbruch, Andreas · Inventors: Radbruch, Andreas
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Magnetofluorescent liposomes are size selected by membrane extrusion and magnetic separation. The selection process provides a highly fluorescent population of liposomes, which are used as a fluorescent labeling agent. Intensity of fluorescent staining can be increased 100-1000-fold without increased background fluorescence, when compared to conventional fluorochromeconjugated antibodies. The highly sensitive staining permits detection of cell surface markers expressed at low levels on the cell surface. Of particular interest is the detection of normally secreted certain cytokines e.g. , interferon .gamma. and IL-10 on the surface of lymphocytes. Cells that are positive for surface …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 18, 1997. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended July 18, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 18, 2019.
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Timeline
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.