Methodology to produce, purify and assay polypeptides with the proteolytic activity of the hcv ns3 protease
CA 2228265 C · Owner: Pessi, Antonello · Inventors: Tomei, Licia; Taliani, Marina; De Francesco, Raffaele
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The process according to the present invention allows expression and isolation of polypeptides with the proteolytic activity of HCV NS3 protease in a pure catalytically active form, and in amounts that are sufficient for discovery of NS3 protease inhibitors and for determination of the three-dimensional structure of the NS3 protease. A further subject of the present invention is a procedure that defines the chemical and physical conditions necessary for completion of the proteolytic activity of the above polypeptides. The invention further comprises new compositions of matter (expression vectors) containing nucleotide sequences capable of expressing the above mentioned polypeptides …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 20, 1996 and granted August 13, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended August 20, 2016.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 20, 2018.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.