Triazole antifungal agents

Abstract From the Canadian patent

An antifungal agent of the formula:-, (see formula I) or a pharmaceutically acceptable salt thereof where Ar is a phenyl group substituted by 1 to 3 substituents each independently, selected from halo and CF3; and X is a group of the formula:-, wherein "Het" is selected from (a) an unsubstituted 1,2,3-triazol-1-yl group (b) an, unsubstituted 1,2,4-triazol-1-yl or -4-yl group (c) a 1,2,3- or 1,2,4-, triazolyl group attached to the adjacent phenyl group by a carbon atom and optionally substituted , on a nitrogen atom by C1-C4 alkyl or (C1-C4 alkoxy)methyl, (d) unsubstituted imidazol-1-yl, (e) an unsubstituted pyrazol-3-yl group an unsubstituted , pyrazol-4-yl, group or 1-methylpyrazol-5-yl …