A novel maturation-inhibited protein kinase

Abstract From the Canadian patent

The present invention provides nucleic acid and amino acid sequences for a novel human MAP kinase expressed in Pisaster ochraceus. The present invention also provides PCR oligomers and hybridization probes for the detection or amplification of nucleotide sequences encoding the kinase; antisense molecules to the nucleotide sequences which encode the kinase; diagnostic tests based on sequences encoding the kinase; genetically engineered expression vectors and host cells for the production of the kinase antibodies capable of binding specifically to the kinase and agonists and inhibitors with specific binding activity for the kinase.