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Expired Canadian patentCanada

Pertussis outer membrane protein

CA 2224052 C · Owner: Tan, Larry · Inventors: Vose, John; Chong, Pele; Fahim, Raafat

CIPO record

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Abstract From the Canadian patent

Pertactin (formerly 69 kDa protein) is recovered in stable biologically pure form having no detectable adenylate cyclase activity from fermentation broth from the fermentation of Bordetella pertussis as well as from the cells. The broth is processed to selectively remove pertussis toxin (PT) and filamentous haemagglutinin (FHA), the pertactin is precipitated by ammonium sulphate and the precipitate is dissolved in buffer at pH 6.0 to 8.5, the solution then is passed through hydroxyapatite and Q-Sepharose chromatograph columns before final ultrafiltration. Cells are extracted with urea and the extract ultrafiltered and diafiltered. The pertactin is precipitated from the extract and the …

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed April 3, 1991 and granted December 18, 2001. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 3, 2011.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 3, 2013.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledApril 3, 1991
GrantedDecember 18, 2001
Term endedApril 3, 2011
Patent numberCA 2224052 C
Classification (IPC)C07K14/23 +2 more

Timeline

Timeline From CIPO dates

1992199419961998200020022004200620082010Application filedApril 3, 1991Patent grantedDec 18, 2001Term endedApril 3, 2011

Sources & verification

Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.