Substituted vinylurea derivatives and medicine containing the same

Abstract From the Canadian patent

Disclosed herein are substituted vinylurea derivatives represented by the following general formula (1):, (1), wherein R1 and R3 are independently a phenyl group which may be substituted, R2 is a phenyl group which may be substituted, or a cycloalkyl group, and wave lines mean that the bonding state may be either E or Z with the, proviso that the cases where R1 R2 and R3 are, unsubstituted phenyl groups and where R1 and R2 are, unsubstituted phenyl groups and R3 is a 4-ethoxyphenyl group are excluded, or salt thereof, and medicines comprising such a derivative as an active ingredient as well as a method of preventing and treating arteriosclerosis with such a medicine. The derivatives or …