Multiple unit sustained release dosage form

Abstract From the Canadian patent

A multiple unit oral pharmaceutical dosage form having a plurality of pellets in a water soluble capsule or in a tablet compressed from the pellets wherein, each pellet contains (a) a substantially inert core (b) an active ingredient layer over, the inert core and containing (i) a pharmacologically active particulate activeingredient (ii) a nonembedding amount of a binder for adhering the active ingredient over the inert core, and optionally (iii) a pharmaceutically acceptable inert adjuvant, such as colloidal silica and (c) a coating over the active ingredient layer for retarding the release of the active ingredient from the active ingredient layer into an aqueous body fluid solvent in …