Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas as 5-lipoxygenase inhibitors

Abstract From the Canadian patent

The present invention provides a compound of formula (I) wherein Ar is (a) , phenyl, naphthyl and biphenyl each optionally substituted, with C1-4 alkyl C1-4 haloalkyl, C1-4 hydroxyalkyl, C1-4 alkoxy C1-4 , haloalkoxy, C2-4 alkoxyalkoxy, C1-4 alkylthio hydroxy, halo, cyano, amino, C1-4 alkylamino di (C2-8) alkylamino, C2-6 alkanoylamino carboxy, C2-, 6 alkoxycarbonyl, or optionally substituted phenyl phenoxy, phenylthio or phenylsulfinyl or (b) furyl benzobfuryl, thienyl, benzobthienyl, pyridyl or quinolyl each optionally substituted with C1-4, alkyl C1-4 haloalkyl, halo, C1-4 alkoxy, optionally-substituted phenyl phenoxy or phenylthio, X is C1-C4 alkylene C2-C4 alkenylene, …