Colchicine derivatives and the therapeutical use thereof
CA 2201723 C · Owner: Indena S.P.A. · Inventors: Bombardelli, Ezio; Gabetta, Bruno
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to novel colchicine derivatives of formula (1) where Y is a -CH2-CH-NH-R3 group or a -CH-CH2OR3 group and the other variables are as defined in claim 1, having antiproliferative antitumoral and anti-, inflammatory activities. The novel compounds have a cytotoxicity on human tumoral cell lines comparable with colchicine but, in comparison with the , latter, they are less toxic and more selective particularly on cells , resistant to the usual medicaments. Some compounds have a marked activity on TNF and interleukine 2, and therefore are very potent anti-inflammatory agents. They can be included in pharmaceutical formulations useful for the parenteral, oral …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 27, 1995 and granted March 25, 2003. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended September 27, 2015.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 27, 2017.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.