Method for cleaving chimeric protein using processing enzyme
CA 2198966 C · Owner: Asubio Pharma Co. Ltd. · Inventors: Masuda, Toyofumi; Suzuki, Yuji; Magota, Koji
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A chimeric protein is provided which comprises a target protein and has been designed so as to be easily cleaved by a processing enzyme, permitting a target protein to be efficiently recovered. The chimeric protein is represented by the following formula:, A-L-B, wherein A represents a protective peptide; B represents a target peptide; and, L represents a linker peptide having the sequence X1-X2-(Pro, Lys, or Arg)-Arg, wherein X1 and X2 represent any amino acid, in its C-terminal region and a domain rich in His in its N-terminal region.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 3, 1997 and granted June 21, 2011. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended March 3, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 3, 2019.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.