Solid support reagents for the synthesis of 3'-nitrogen containing polynucleotides
CA 2197302 C · Owner: The Perkin-Elmer Corporation · Inventors: Fung, Steven; Woo, Sam L.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention is directed toward a polynucleotide synthesis support for use in automated polynucleotide synthesis of 3'-nitrogen functionalized polynucleotides. The invention includes in one aspect, a polynucleotide , synthesis reagent having structure (I) where T is an acid-cleavable hydroxyl protecting group; Q is a linker connecting the nitrogen and oxygen; R1 is a nitrogen substituent; R2 through R4 are separately hydrogen or lower alkyl; Y is an atom which is electronegative with respect to carbon; X1 is an atom which is electronegative with respect to carbon; Z is a bond or spacer arm; and W is a derivatized solid synthesis support capable of linking to Z. In a second …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 18, 1995 and granted May 20, 2003. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended July 18, 2015.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 18, 2017.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.