Controlled local delivery of chemotherapeutic agents for treating solid tumors
CA 2196304 C · Owner: Brem, Henry · Inventors: Brem, Henry; Langer, Robert S.; Domb, Abraham J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A method and devices for localized delivery of a chemotherapeutic agent to solid tumors, wherein the agent does not cross the blood--brain barrier and is characterized by poor bioavailability and/or short half-lives in vivo, are described. The devices consist of reservoirs which release drug over an extended time period while at the same time preserving the bioactivity and bioavailability of the agent. In the most preferred embodiment, the device consists of biodegradable polymeric matrixes, although reservoirs can also be formulated from non--biodegradable polymers or reservoirs connected to implanted infusion pumps. The devices are implanted within or immediately adjacent the …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 2, 1995 and granted February 15, 2011. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended August 2, 2015.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 2, 2017.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.