Process for the synthesis of nabumetone
CA 2194414 C · Owner: Bianchi, Stefano · Inventors: Cannata, Vincenzo; Bianchi, Stefano; Bertoni, Amilcare
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
New process for the synthesis of the antiinflammatory drug known as nabumetone that consists in reacting 2-acetyl-5-bromo-6methoxynaphthalene with an alkyl acetate in presence of an alkaline alcoholate to get4-(5-bromo-6-methoxy-2-naphthyl)-4-hydroxybut-3-en-2one that by catalytic hydrogenation in a polar solvent and in presence of a base gives 4-(6-methoxy-2-naphthyl)butan-2-one known as nabumetone.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 6, 1997 and granted December 25, 2001. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended January 6, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 6, 2019.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.