Stable oil-in-water emulsions incorporating a taxine (taxol) and method of making same
CA 2194226 C · Owner: Fuhrhop, Ralph W. · Inventors: Fuhrhop, Ralph W.; Richard, Thomas J.; Kaufman, Robert J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention is directed to a composition of a taxine in a stable oil-inwater emulsion for intravenous administration. The invention also relates to a method for incorporating a taxine into an oil and making a stable oil-in-water emulsion. The composition includes a taxine an oil, water and a surfactant. , In a preferred embodiment the taxine is taxol, the oil is safflower oil and the surfactant is lecithin. The taxine is incorporated into the oil by dissolving the taxine in a solution of an oil and a taxine co-solvent such as , isopropanol, for example. The co-solvent then is removed to form a solution of the taxine in oil. This solution may be dispersed in water with a surfactant …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 22, 1995 and granted October 24, 2000. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended June 22, 2015.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 22, 2017.
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.