Uses for corticotropin releasing factor atagonists

Abstract From the Canadian patent

Disclosed is a pharmaceutical composition for treating, preventing or inhibiting cardiovascular or heart related diseases, comprising (a) a compound of the formula or , I II, or a pharmaceutically acceptable salt thereof wherein A is N or CR7 (in which R7 is H alkyl, halo or the, like), B is -NR1R2 -CR1 R2R11 or the like (in which R1 is H or alkyl, R2 is alkyl, aryl, arylalkyl cycloalkyl or the like, and R11 is H, OH or the like) D is N, -CR10 (in which R10 is, H, alkyl halo or the like ), C=O, -C=NH, etc.), E is -CR4 (in which R4 is H, alkyl, halo etc.), N, -NR6 or -CR4R6 (in which R4 is H, alkyl, halo, etc. and R6 is H or alkyl) Y is N or, CH, Z is O, S, NH, ect. R3 is H alkyl, halo, etc. …