.alpha.-1-antichymotrypsin analogues having chymase inhibiting activity
CA 2186635 A1 · Owner: The Trustees Of The University Of Pennsylvania · Inventors: Wang, Zhi Mei; Rubin, Harvey; Cooperman, Barry S.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention provides analogues of .alpha.-1-antichymotrypsin having amino acid substitutions at positon 358. .alpha.-1-antichymotrypsin analogues having amino acid substitutions at positions 356-361 and analogues having amino acid substitutions at positions 356-361 wherein the amino acid at position 358 is substituted are also within the scope of the invention. These analogues exhibit chymase inhibitory activity. Also provided are novel .alpha.-1-antichymotrypsins having an N-terminal extension of methionine-alanine-serine or alanine-serine. Expression vectors for the production of .alpha.-1-antichymotrypsins are also provided. The present invention also provides host cells and cell …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 29, 1994. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended April 29, 2014.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 29, 2016.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.