Treatment of platelet derived growth factor related disorders such as cancers using inhibitors of platelet derived growth receptor
CA 2180658 C · Owner: Orfi, Laszlo · Inventors: Hirth, Klaus Peter; Schwartz, Donna Pruess; Mann, Elaina
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention concerns compounds which can inhibit platelet derived growth factor receptor (PDGF-R) activity preferably, such compounds also inhibit the activity of other members of the PDGF-R super family and are selective for members of the PDGF-R super family. The PDGF-R super family includes PDGF-R and PDCF-R related kinases Flt and KDR. The featured compounds are active on cell cultures to reduce the activity of the PDGF-R and preferably one or more PDGF-R related kinases. An example of a featured compound, A10 (see Figure 1A), and its ability to inhibit growth of tumor cells in vivo is described below. Using the present application as guide other compounds able to inhibit …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 6, 1995 and granted March 28, 2000. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended January 6, 2015.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 6, 2017.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.