Isolated p27 protein and its encoding nucleic acid molecules
CA 2180570 C · Owner: Massague, Joan · Inventors: Massague, Joan; Polyak, Kornelia; Koff, Andrew
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The subject invention provides an isolated protein having an apparent molecular weight of about 27 kD and capable of binding to and inhibiting the activation of a cyclin E-Cdk2 complex. The subject invention also provides the nucleic acid encoding the p27 protein vectors, and host cells for producing the recombinant form of the p27 protein. The subject invention further provides methods for identifying agents capable of modulating the ability of p27 to inhibit the activation of the cyclin E-Cdk2 complex. Finally the subject invention provides, methods for treating subjects diagnosed with hypoproliferative disorders using said agents.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 9, 1995 and granted March 26, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended January 9, 2015.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 9, 2017.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.