Nucleic acid analogue induced transcription of double stranded dna
CA 2176746 C · Owner: Egholm, Michael · Inventors: Nielsen, Peter Eigil; Egholm, Michael; Berg, Rolf-Henrik
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
RNA is transcribed from a double, stranded DNA template by forming a complex by hybridising to the template at a desired transcription initiation site one or more oligonucleic acid analogues of the PNA type capable of forming a transcription initiation site with the DNA and exposing the complex to the action of a DNA dependant RNA, polymerase in the presence of nucleoside triphosphates. Equal length transcripts may be obtained by placing a block to transcription downstream from the initiation site or by cutting the template at such a selected location The initiation site is formed by displacement of one strand of the DNA locally by the PNA hybridisation.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 22, 1994 and granted August 8, 2000. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended November 22, 2014.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 22, 2016.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.