Method for detecting charged oligonucleotides in biological fluids
CA 2176341 A1 · Owner: Bourque, Andre · Inventors: Bourque, Andre; Cohen, Aharon S.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Disclosed is a method for detecting and quantitating oligonucleotides with charged internucleotide linkages in biological fluids. In this method,'a biological fluid sample is contacted with an anion exchange resin at from 40 °C to 65 °C for a time sufficient to enable oligonucleotides in the sample to adsorb to the resin. The adsorbed oligonucleotides are then desorbed with a buffer having a salt concentration of about 1 M to 2.5 M and a pH in the range of about 6.5 to 7.5 the desorption being performed at about 40 - 65 °C. The oligonucleotides so released are then detected and quantitated.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 15, 1994. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended November 15, 2014.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 15, 2016.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.