Process for generating specific antibodies
CA 2175482 A1 · Owner: Genzyme Corporation · Inventors: Hillhouse, Dana; Copeland, Diane P.; Barsomian, Gary
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to a method for generating an antibody which is specific for an immunorecessive epitope and nucleic, acid encoding the antibody. The Subject method generally comprises the steps of generating a variegated display library of antibody variable regions and selecting from the library those antibody variable regions which have a desired binding specificity for the immunorecessive epitope. The antibody variable regions used to generate the display library are cloned from an immunotolerance-derived antibody repertoire.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 8, 1994. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 8, 2014.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 8, 2016.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.