Tumor suppressor genes, proteins encoded thereby and use of said genes and proteins
CA 2174136 A1 · Owner: Yeda Research And Development Co. Ltd. · Inventors: Kimchi, Adi
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention is based on the pioneering finding that inhibition of expression of certain genes counteracts the cytokine-induced cell death. As long as these genes function normally cytokine induces cell death; once the expression of said genes in inhibit the cytokine-, induced cell death is inhibited. It follows therefrom that the normal expression is cytokine-induced cell death. In HeLa cells IFN-y induces a biphasic process, which comprises an initial cytostatic phase and a subsequent cytotoxic phase (programmed cell death). The novel genes discovered in accordance with the present invention were found to affect only the later cytotoxic phase. These genes, referred to as "DAP" …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 12, 1994. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended October 12, 2014.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 12, 2016.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.