Method of inducing and maintaining neuronal cells
CA 2174098 C · Owner: Melton, Douglas A. · Inventors: Hemmati-Brivanlou, Ali; Melton, Douglas A.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention makes available a method for inducing neuronal differentiation and preventing the death or degeneration of neuronal cells both in vitro and in vivo. The subject method stems from the unexpected finding that contrary to traditional unterstanding, of neural induction the default fate of ectodermal tissue is neuronal rather than mesodermal and/or epidermal. In particular it has been, discovered that preventing or antagonizing a signaling pathway in a cell for a growth factor of the TGF-.beta. family can result in neuronal differentiation of that cell.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 14, 1994 and granted January 25, 2011. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended October 14, 2014.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 14, 2016.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.