Chiral synthesis with modified enzymes
CA 2127126 A1 · Owner: Genzyme Limited · Inventors: Wilks, Helen M.; Holbrook, Joseph J.; Elhawrani, Ayman
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A method for modifying the specificity and/or efficiency of an enzyme, while retaining its catalytic activity characterised in, that it comprises: selecting an enzyme the tertiary structure of, which is substantially known or deduced; identifying at least one specificity and/or efficiency-related region; identifying or constructing unique restriction sites bounding the identified region in the DNA coding therefor; generating a DNA sequence which corresponds to at least a portion of the identified region except, that the nucleotides of at least one codon are randomized or, selecting as a substitute for at least a portion of the identified region an alternative such region, which may itself …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 29, 1993. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended January 29, 2013.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 29, 2015.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.