Jak kinases and regulation of cytokine signal transduction
CA 2126523 A1 · Owner: St. Jude Children'S Research Hospital · Inventors: Witthuhn, Bruce A.; Quelle, Frederick W.; Silvennoinen, Ollie
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Jak Kinases and Regulation of Cytokine Signal Transduction, Abstract, The present invention is based on the discovery that a critical step in the cellular response to several cytokines is the activation (i.e. tyrosine phosphorylation) of a member of the Jak kinase family. In particular several, cytokines whose activity is mediated by the activation of Jak2 kinase are identified. The present invention provides novel methods for regulating the cellular response to these cytokines by inhibiting or enhancing the Jak kinase activity which mediates the response. Assays for identifying inhibitors of Jak kinase activity or cytokine-induced Jak kinase activation useful in the methods of the …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 22, 1994. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended June 22, 2014.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 22, 2016.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.