Method for preparing taxane derivatives
CA 2126462 C · Owner: Aventis Pharma S.A. · Inventors: Mas, Jean-Manuel; Fouque, Elie
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Method for preparing taxane derivatives of general formula (I) by esterification at a temperature between -10 and 60 DEG C of a derivative of baccatine III or 10-deacetyl baccatine III of general formula (II) by means of an acid of general formula (III) followed by replacement of the protective groupings G1 G2 and R2 of the resulting product by hydrogen atoms. In formulae (I) (II) or (III), Ar stands for an aryl radical; R stands for hydrogen or acetyl; R1 is benzoyl or tert.butoxycarbonyl; G1 is a hydroxy function protective grouping G2 stands for the acetyl radical or a hydroxy function protective grouping and R2 stands for a hydroxy function protective grouping.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed February 4, 1993 and granted July 9, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended February 4, 2013.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 4, 2015.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.