2-amino-1,3-propanediol compound and immunosuppressant

Abstract From the Canadian patent

2-Amino-1,3-propanediol compounds of the formula (I) (see formula I), wherein R is an optionally substituted straight- or branched carbon chain, an optionally substituted aryl an optionally, substituted cycloalkyl or the like and R2, R3, R4 and R5 are, the same or different and each is a hydrogen an alkyl, an, aralkyl, an acyl or an alkoxycarbonyl pharmaceutically, acceptable salts thereof and immunosuppressants comprising these compounds as active ingredients. The 2-amino-1,3-propanediol compounds of the present invention show immunosuppressive action and are useful for suppressing rejection in organ or bone marrow tranplantation prevention and treatment of autoimmune diseases or as …