Process for preparing and purifying alpha-interferon
CA 2124271 A1 · Owner: Voss, Tilman · Inventors: Falkner, Edgar; Bodo, Gerhard; Maurer-Fogy, Ingrid
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to a new process for preparing recombinant IFN-.alpha.. Expression in E. coli is carried out under the control of a phoA promotor. By linking the IFN-.alpha. gene with the STII signal sequence the secretion, of the protein into the periplasmic space and a correctly processed N-terminus are obtained. Purification of the protein is carried out by adsorption chromatography on silica gel, hydrophobic interaction chromatography, cation and anion exchange chromatography.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 25, 1994. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 25, 2014.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 25, 2016.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.