1-amino-2-(benzothiazolyl)methyl spiro isoquinoline-4(1h),3'-pyrrolidine-1,2',3,5'(2h)- tetrones and analogs thereof useful as aldose reductase inhibitors
CA 2122916 A1 · Owner: American Home Products Corporation · Inventors: Malamas, Michael S.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention concerns compounds of formula (I) wherein: R1 R2 and R3 are independently hydrogen, alkyl containing 1 to 6 carbon atoms, halogen, lower alkoxy containing 1 to 6 carbon atoms, trifluoromethyl or nitro; R6 is (a) (b) or (c) wherein R4 , and R5 are independently hydrogen alkyl containing 1 to 6, carbon atoms, aryl aryl (lower alkyl) wherein aryl contains 6 to 10 carbons atoms and lower alkyl contains 1 to 6 carbon atoms alkanoyl of 2 to 5 carbon atoms or carboalkoxy or R4 and R5 are, joined to form alicyclic or heterocyclic rings selected from the group consisting of (d) wherein n = 1-10; (e) wherein X = O S, SO, SO2; (f) wherein X = O, S; and (g) wherein R9 = H lower, alkyl …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 25, 1992. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended November 25, 2012.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 25, 2014.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.