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Expired Canadian patentCanada

Heparinase gene from flavobacterium heparinum

CA 2122004 C · Owner: Cooney, Charles L. · Inventors: Langer, Robert S.; Cooney, Charles L.; Moremen, Kelley

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Abstract From the Canadian patent

The cloning of the heparinase gene from Flavobacterium Heparinum using the polymerase chain reaction is described. The Open Reading Frame (ORF) corresponded to 1152 base pairs encoding a precursor protein of MW 43,800 daltons. The amino acid sequence reveals a 20-residue leader peptide. The gene was expressed in two expression systems in E. Coli.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed October 22, 1992 and granted August 19, 2003. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended October 22, 2012.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 22, 2014.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledOctober 22, 1992
GrantedAugust 19, 2003
Term endedOctober 22, 2012
Patent numberCA 2122004 C
Classification (IPC)C12N15/60 +2 more

Timeline

Timeline From CIPO dates

1993199519971999200120032005200720092011Application filedOct 22, 1992Patent grantedAug 19, 2003Term endedOct 22, 2012

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.