Therapeutic conjugates of toxins and drugs
CA 2118032 C · Owner: Immumomedics, Inc. · Inventors: Goldenberg, David M.; Griffiths, Gary L.; Hansen, Hans J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A conjugate useful in cancer or infectious disease therapy is a drug or modified toxin which is a native toxin devoid of a functioning receptor binding domain and a protein which reacts with a substance associated with a targeted cell or pathogen. The targeted substance internalizes the conjugate into the cell cytoplasm and then kills the cell. The protein prior to conjugation has at least one mercapto group which becomes a site for conjugation to the toxin or drug. Also provided are methods for producing the conjugate, pharmaceutical compositions of the conjugate and uses of the conjugate to prepare medicaments useful in therapy. .
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 7, 1993 and granted September 29, 1998. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended May 7, 2013.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 7, 2015.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.