Enhancement of ribozyme catalytic activity by a neighboring facilitator oligonucleotide
CA 2117428 A1 · Owner: Worcester Foundation For Experimental Biology · Inventors: Goodchild, John
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Methods are disclosed for increasing ribozyme catalytic activity without reducing specificity which methods comprise, contacting an RNA molecule with a ribozyme and a facilitator oligonucleotide. The present invention further provides compositions comprising a ribozyme and an effective amount of a facilitator oligonucleotide. Methods are also disclosed for reducing the concentration of Mg2+ and Mn2+ required by a ribozyme to catalytically cleave target RNA.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed February 4, 1993. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended February 4, 2013.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 4, 2015.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.