Compositions of iodobenzoic acid derivatives in film-forming materials for visualization of the gastrointestinal tract

Abstract From the Canadian patent

Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising a polymeric material capable of forming a coating on the gastrointestinal tract and an x-ray producing agent of the formula wherein, Z= H, halo, C1-C20 alkyl, cycloalkyl lower alkoxy, cyano, where, the Alkyl and cycloalkyl groups can be substituted with halogen or halo-lower-alkyl groups;, R= C1-C25 alkyl cycloalkyl, or halo-lower-alkyl, optionally substituted with halo, fluoro-lower-alkyl aryl, lower-alkoxy, hydroxy, carboxy, lower-alkoxy carbonyl or lower-alkoxycarbonyloxy, (CR1R2)p-(CR3=CR4)mQ,or(CR1R2)p-C?C-Q; R1, R2, R3 and R4 are independently lower-alkyl optionally, …