Methods of treatment of motor neuron diseases using members of the bdnf/nt-3/ngf family of molecules
CA 2113083 A1 · Owner: Radziejewski, Czeslaw · Inventors: Wong, Vivien; Radziejewski, Czeslaw; Distefano, Peter
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to methods of treatment of motor neuron disorders, such as amyotrophic lateral sclerosis (Lou Gehrig's disease) comprising administering to a patient in need of, such treatment an effective amount of a neurotrophic factor that is a member of the BDNF/NT-3/NGF family of molecules and that supports the survival, growth and/or differentiation of motor neurons. It is based in part, on the discovery that BDNF and NT-3 are each able to increase choline acetyltransferase activity in motor neuron cultures. In preferred, specific embodiments of the invention, a combination of BDNF or NT-3 and a second agent such as, CNTF, may be used in the treatment of motor neuron …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 19, 1992. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 19, 2012.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 19, 2014.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.