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Asymmetric hydrogenation of dihydrofuroimidazole derivatives

CA 2111663 A1 · Owner: Eyer, Martin · Inventors: Fuchs, Rudolf; Eyer, Martin; Mcgarrity, John

CIPO record

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Abstract From the Canadian patent

A process for asymmetric hydrogenation of a dihydrofuroimidazole derivative of the general formula (I): I, wherein R1 represents a cleavable protective group and R2 represents hydrogen or a cleavable protective group with, hydrogen in the presence of a homogeneous catalyst to produce the corresponding diastereomeric tetrahydrofuroimidazole derivative of the general formula (II):, II, Tetrahydrofuroimidazole derivatives of the general formula II are intermediate products for the production of vitamin (+)-biotin.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed December 16, 1993. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 16, 2013.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 16, 2015.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledDecember 16, 1993
GrantedNo grant recorded
Term endedDecember 16, 2013
Patent numberCA 2111663 A1
Classification (IPC)C07D491/04 +1 more

Timeline

Timeline From CIPO dates

1994199619982000200220042006200820102012Application filedDec 16, 1993Term endedDec 16, 2013

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.