Insertional mutations in mycobacteria
CA 2111217 A1 · Owner: Albert Einstein College Of Medicine, A Division Of Yehiva University · Inventors: Kalpana, Ganjam V.; Bloom, Barry; Jacobs, William R.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A mutated mycobacterium selected from the class consisting of mutated M.bovis-BCG, mutated M.tuberculosis and mutated, M.leprae. The mutation of M.bovis-BCG M.tuberculosis, or M.leprae is preferably effected through an insertional mutation of a mycobacterial gene. The insertional mutagenesis may be effected, for example, through illegitimate recombination or by a mycobacterial transposon. Such mutated mycobacteria may then be transformed with an expression vector(s) containing a complement gene to the gene which is mutated, and preferably also including a heterologous gene.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 2, 1992. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended June 2, 2012.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 2, 2014.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.