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The use of pasteurella haemolytica glycoprotease in a process for recovering cells rich in o-glycosylated surface portions

CA 2108565 A1 · Owner: Sutherland, Robert D. · Inventors: Sutherland, Robert D.; Mellors, Alan

CIPO record

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Abstract From the Canadian patent

A method for recovering viable cells having surface protein determinants having portions rich in O-glycosylated carbohydrates is provided. The proteins have determinants which are substrate sensitive to a P. haemolytica derived, neutralmetallo-glycoprotease. The glycoprotease has highly restricted specificity for cleaving solely from the cell surfaces the O-glycosylated protein portions having the determinants while retaining cell viability. The process comprises: i) contacting the cells in solution with affinity matrices which bind specifically to one or more of the determinants which are part of the glycoprotease sensitive substrates the affinity matrices are allowed to bind to the …

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed December 20, 1991. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 20, 2011.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 20, 2013.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledDecember 20, 1991
GrantedNo grant recorded
Term endedDecember 20, 2011
Patent numberCA 2108565 A1
Classification (IPC)C12N5/07 +2 more

Timeline

Timeline From CIPO dates

1992199419961998200020022004200620082010Application filedDec 20, 1991Term endedDec 20, 2011

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.