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Expired Canadian patentCanada

Osteoinductive protein mixtures and purification processes

CA 2107481 C · Owner: Sulzer Orthopedics Biologics Inc. · Inventors: Poser, James W.; Benedict, James J.

CIPO record

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Abstract From the Canadian patent

A method for purifying bone-derived osteoinductive factors including an ultrafiltration process, an anion exchange process, a cation exchange process, and a reverse phase HPLC process. The ultrafiltration process preferably includes a first ultrafiltration step using a membrane having a nominal molecular weight cutoff of approximately 100 kilodaltons (kD) and a second ultrafiltration step employing a membrane having a nominal molecular weight cutoff of approximately 10 kD. For the anion exchange process, a strongly cationic resin is used preferably having , quaternary amine functional groups. Typically the eluant, for the anion exchange process has a conductivity from about 10,260 …

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed April 21, 1992 and granted December 3, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 21, 2012.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 21, 2014.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledApril 21, 1992
GrantedDecember 3, 2002
Term endedApril 21, 2012
Patent numberCA 2107481 C
Classification (IPC)A61K38/18 +2 more

Timeline

Timeline From CIPO dates

1993199519971999200120032005200720092011Application filedApril 21, 1992Patent grantedDec 3, 2002Term endedApril 21, 2012

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.