Bradykinin type peptides
CA 2106768 C · Owner: Hiner, Roger N. · Inventors: Hiner, Roger N.; Kyle, Donald J.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The substitution of the L-Pro at the 7-position with D-Phe or D-Tic and substitution of the L-Phe at the 8-position with hydroxyproline ethers and thioethers of the peptide hormone bradykinin and other additional substituted analogs of bradykinin converts bradykinin agonists into bradykinin antagonists. The invention further provides additional modifications at other positions within the novel 7- and 8-position modified bradykinin antagonists, which increase enzyme resistance antagonist potency, and/or specificity of the new bradykinin antagonists. The analogs produced are useful in treating conditions and diseases of a mammal and human in which an excess of bradykinin or related kinins …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 16, 1992 and granted September 19, 2000. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 16, 2012.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 16, 2014.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.