Method of inhibiting padgem-mediated interactions using an inhibitor comprising a 2,6 sialic acid component
CA 2105997 A1 · Owner: Gilbert, Gary E. · Inventors: Larsen, Eric; Palabrica, Theresa; Gilbert, Gary E.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to a method of inhibiting (reducing or preventing) the interaction or adhesion of a PADGEM-bearing cell with a cell bearing a PADGEM ligand by contacting the PADGEM-bearing cell with an inhibitor comprising a 2,6-linked sialic acid component. By the method of the present invention it is possible to, inhibit the interaction of a PADGEM-bearing cell such as a, platelet or endothelial cell with a cell bearing a PADGEM ligand, such as a white blood cell (leukocyte) by contacting the cell with an inhibitor comprising a 2,6-linked sialic acid residue. The invention further relates to inhibitors useful in the present method.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 9, 1992. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 9, 2012.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 9, 2014.
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.