Monoclonal antibody against lps core
CA 2105979 C · Owner: Common Services Agency · Inventors: Di Padova, Franco; Barclay, George R.; Poxton, Ian R.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
By use of the Köhler/Milstein procedure involving immunization of mice with a number of different rough strains of heatkilled Gram-negative bacteria followed by fusion and suitable screening of the resulting hybridomas, murine monoclonal antibodies are obtained which are cross-protective against endotoxemia caused by at least two different Gram-negative bacterial strains having different core structures. The murine MAbs may be chimerized or humanized by known methods. The preferred product is a chimeric MAb of IgG isotype in which the hypervariable regions of the heavy chain have the amino acid sequences: Asp Tyr Tyr Met Thr; Leu Ile Arg Asn Lys Arg Asn Gly Asp Thr Ala Glu Tyr Ser Ala …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed February 22, 1992 and granted May 13, 2003. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended February 22, 2012.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 22, 2014.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.