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Bicyclopolyazamacrocyclocarboxylic acid complexes their conjugates, processes for their preparation, and use as radiopharmaceuticals

CA 2103553 A1 · Owner: Kiefer, Garry E. · Inventors: Simon, Jaime; Kiefer, Garry E.

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Abstract From the Canadian patent

Complexes of bicyclopolyazamacrocyclocarboxylic acid compounds with a metal ion, e.g. 153Sm, 177Lu, 159Gd 149Pm, 140La, 175Yb, 166Ho, 90Y, 47Sc, 186Re 188Re, 142Pr, 99mTc, 67Ga, 68Ga, 105Rh 97Ru, 111In, 113mIn or, 115mIn ion, are disclosed. The complexes can be covalently attached to a biologically active molecule, e.g. an antibody or antibody fragment, to form conjugates. The complexes and conjugates are useful as radiopharmaceutical agents for therapy and/or diagnostic purposes. Processes to prepare the complex and conjugate are discussed.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed December 10, 1992. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 10, 2012.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 10, 2014.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledDecember 10, 1992
GrantedNo grant recorded
Term endedDecember 10, 2012
Patent numberCA 2103553 A1
Classification (IPC)C07K16/00 +2 more

Timeline

Timeline From CIPO dates

1993199519971999200120032005200720092011Application filedDec 10, 1992Term endedDec 10, 2012

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.