Novel immunosuppressive compounds
CA 2102178 A1 · Owner: Duffy, John P. · Inventors: Duffy, John P.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention relates to anovel class of immuno-suppressive compounds having an affinity for the FK-506 binding protein (FKBP). Once bound to this protein the immunosuppressive compounds, inhibit the prolyl peptidyl cis-trans isomerase (rotamase) activity of the FKBP and inhibit T cell activation. As such the compounds of, this invention can be used as immunosuppressive drugs to prevent or significantly reduce graft rejection in bone marrow and organ transplantations and for use in the treatment of a wide variety of autoimmune diseases in humans and other mammals.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 26, 1992. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 26, 2012.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 26, 2014.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.