Mixed specificity fusion proteins
CA 2099779 C · Owner: Aruffo, Alejandro A. · Inventors: Aruffo, Alejandro A.; Damle, Nitin K.; Ledbetter, Jeffrey A.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Mixed specificity fusion proteins capable of binding to cellular adhesion molecules have been produced. The fusion proteins contain a polypeptide region, such as an IgG constant region operatively attached to at least two binding regions each of which corresponds to either an extracellular domain of a cell surface receptor for cellular adhesion molecules, or a variable region of an antibody directed to a cellular adhesion molecule. A method of inhibiting inflammation in a patient is disclosed in which the present fusion proteins are administered to a patient to inhibit the attachment of inflammatory cells to vascular endothelium. A method of inhibiting metastasis is disclosed in which …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 24, 1992 and granted March 19, 2002. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended January 24, 2012.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 24, 2014.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.